Israel to perform world’s first human spinal cord transplant
Israel to perform world’s first human spinal cord transplant
Israel is preparing to perform the world’s first human spinal cord transplant using a patient’s own cells, a medical breakthrough that could enable paralysed individuals to stand and walk again.
Tel Aviv University made the announcement on Wednesday, describing the upcoming surgery as a historic milestone in regenerative medicine.
Globally, more than 15 million people live with spinal cord injuries, most of which result from road accidents, falls, or violence. Current treatment focuses on stabilising patients and rehabilitation, as there is no cure that restores full spinal cord function.
Leading the groundbreaking procedure is Professor Tal Dvir, head of the Sagol Center for Regenerative Biotechnology at Tel Aviv University and chief scientist at Israeli biotech firm Matricelf.
The process involves reprogramming a patient’s own blood cells into stem-cell-like cells, which are then used to engineer a personalised spinal cord implant.
This lab-grown tissue is designed to fuse with healthy nerves and restore communication between the brain and body.
Animal trials have shown remarkable success, with paralyzed rats regaining the ability to walk after receiving similar implants. Following these results, Israel’s Ministry of Health recently approved “compassionate use” trials in eight patients, making the country the first in the world to attempt such a procedure.
“This is undoubtedly a matter of national pride,” Prof. Dvir said. “Our goal is to help paralyzed patients rise from their wheelchairs. The animal trials showed extraordinary success, and we are hopeful the results in humans will be just as promising.”
Gil Hakim, CEO of Matricelf, added that the breakthrough could redefine spinal cord treatment globally. “This first procedure is more than a scientific breakthrough; it is a step toward transforming an area of medicine long considered untreatable,” he said.
If successful, the surgery could usher in a new era of regenerative medicine, offering fresh hope to millions living with paralysis worldwide.
